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xCT inhibition sensitizes tumors to γ-radiation via glutathione reduction

About 3 million US cancer patients and 1.7 million EU cancer patients received multiple doses of radiation therapy (RT) in 2012, with treatment duration limited by normal adjacent tissue damage. Tumor-specific sensitization could allow treatment with lower radiation doses, reducing normal tissue dam...

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Detalles Bibliográficos
Autores principales: Cobler, Lara, Zhang, Hui, Suri, Poojan, Park, Catherine, Timmerman, Luika A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122354/
https://www.ncbi.nlm.nih.gov/pubmed/30190786
http://dx.doi.org/10.18632/oncotarget.25794