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xCT inhibition sensitizes tumors to γ-radiation via glutathione reduction
About 3 million US cancer patients and 1.7 million EU cancer patients received multiple doses of radiation therapy (RT) in 2012, with treatment duration limited by normal adjacent tissue damage. Tumor-specific sensitization could allow treatment with lower radiation doses, reducing normal tissue dam...
Autores principales: | Cobler, Lara, Zhang, Hui, Suri, Poojan, Park, Catherine, Timmerman, Luika A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122354/ https://www.ncbi.nlm.nih.gov/pubmed/30190786 http://dx.doi.org/10.18632/oncotarget.25794 |
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