Resistance of Leishmania infantum to allopurinol is associated with chromosome and gene copy number variations including decrease in the S-adenosylmethionine synthetase (METK) gene copy number

Leishmania infantum is one of the causative agents of visceral leishmaniasis (VL), a widespread, life-threatening disease. This parasite is responsible for the majority of human VL cases in Brazil, the Middle East, China, Central Asia and the Mediterranean basin. Its main reservoir are domestic dogs...

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Detalles Bibliográficos
Autores principales: Yasur-Landau, Daniel, Jaffe, Charles L., David, Lior, Doron-Faigenboim, Adi, Baneth, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Regular article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122375/
https://www.ncbi.nlm.nih.gov/pubmed/30173105
http://dx.doi.org/10.1016/j.ijpddr.2018.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122375/
https://www.ncbi.nlm.nih.gov/pubmed/30173105
http://dx.doi.org/10.1016/j.ijpddr.2018.08.002

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