Lenalidomide induced durable remission in a patient with MDS/MPN-with ring sideroblasts and thrombocytosis with associated 5q- syndrome

We describe a patient with MDS/MPN with ring sideroblasts and thrombocytosis who had deletions of long arm of chromosome 5 (5q-) and chromosome 20 (20q-). Molecular studies showed an exon 9, frame shift mutation in the calreticulin (CALR) gene, and absence of mutations in JAK2, MPL, SETBP1 or SF3B1....

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Detalles Bibliográficos
Autores principales: Alshaban, Ahmed, Padilla, Osvaldo, Philipovskiy, Alexander, Corral, Javier, McAlice, Meghan, Gaur, Sumit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122386/
https://www.ncbi.nlm.nih.gov/pubmed/30186759
http://dx.doi.org/10.1016/j.lrr.2018.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122386/
https://www.ncbi.nlm.nih.gov/pubmed/30186759
http://dx.doi.org/10.1016/j.lrr.2018.08.001

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