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Lenalidomide induced durable remission in a patient with MDS/MPN-with ring sideroblasts and thrombocytosis with associated 5q- syndrome
We describe a patient with MDS/MPN with ring sideroblasts and thrombocytosis who had deletions of long arm of chromosome 5 (5q-) and chromosome 20 (20q-). Molecular studies showed an exon 9, frame shift mutation in the calreticulin (CALR) gene, and absence of mutations in JAK2, MPL, SETBP1 or SF3B1....
Autores principales: | Alshaban, Ahmed, Padilla, Osvaldo, Philipovskiy, Alexander, Corral, Javier, McAlice, Meghan, Gaur, Sumit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122386/ https://www.ncbi.nlm.nih.gov/pubmed/30186759 http://dx.doi.org/10.1016/j.lrr.2018.08.001 |
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