Homocysteine-lowering gene therapy rescues signaling pathways in brain of mice with intermediate hyperhomocysteinemia

Hyperhomocysteinemia due to cystathionine beta synthase (CBS) deficiency is associated with diverse cognitive dysfunction. Considering the role of the serine/threonine kinase DYRK1A, not only in developmental defects with life-long structural and functional consequences, but also in multiple neurode...

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Detalles Bibliográficos
Autores principales: Baloula, Vanessa, Fructuoso, Marta, Kassis, Nadim, Gueddouri, Dalale, Paul, Jean-Louis, Janel, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122394/
https://www.ncbi.nlm.nih.gov/pubmed/30172984
http://dx.doi.org/10.1016/j.redox.2018.08.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122394/
https://www.ncbi.nlm.nih.gov/pubmed/30172984
http://dx.doi.org/10.1016/j.redox.2018.08.015

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