Suppression of hERG K(+) current and cardiac action potential prolongation by 4-hydroxynonenal via dual mechanisms

Oxidative stress under pathological conditions, such as ischemia/reperfusion and inflammation, results in the production of various reactive chemicals. Of these chemicals, 4-hydroxynonenal (4-HNE), a peroxidation product of ω6-polyunsaturated fatty acid, has garnered significant attention. However,...

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Detalles Bibliográficos
Autores principales: Choi, Seong Woo, Choi, Si Won, Jeon, Young Keul, Moon, Sung-Hwan, Zhang, Yin-Hua, Kim, Sung Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122396/
https://www.ncbi.nlm.nih.gov/pubmed/30172983
http://dx.doi.org/10.1016/j.redox.2018.08.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122396/
https://www.ncbi.nlm.nih.gov/pubmed/30172983
http://dx.doi.org/10.1016/j.redox.2018.08.018

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