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Alleviation of endoplasmic reticulum stress protects against cisplatin-induced ovarian damage
BACKGROUND: Cisplatin (CDDP), a widely used chemotherapeutic agent, can induce excessive granulosa cell apoptosis, follicle loss and even premature ovarian insufficiency (POI). However, the mechanism remains elusive, although some studies have indicated the involvement of endoplasmic reticulum stres...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122480/ https://www.ncbi.nlm.nih.gov/pubmed/30176887 http://dx.doi.org/10.1186/s12958-018-0404-4 |