Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis

BACKGROUND: The MRE11/RAD50/NBS1 (MRN) complex plays an essential role in detecting and repairing double-stranded breaks, and thus the potential roles of MRE11, RAD50 and NBS1 proteins in the pathogenesis of various cancers is the subject of investigation. This study was aimed at assessing the three...

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Detalles Bibliográficos
Autores principales: Ho, Vincent, Chung, Liping, Singh, Amandeep, Lea, Vivienne, Abubakar, Askar, Lim, Stephanie H., Ng, Weng, Lee, Mark, de Souza, Paul, Shin, Joo-Shik, Lee, Cheok Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122630/
https://www.ncbi.nlm.nih.gov/pubmed/30176843
http://dx.doi.org/10.1186/s12885-018-4776-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122630/
https://www.ncbi.nlm.nih.gov/pubmed/30176843
http://dx.doi.org/10.1186/s12885-018-4776-9

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