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N-acetylcysteine as add-on to antidepressant medication in therapy refractory major depressive disorder patients with increased inflammatory activity: study protocol of a double-blind randomized placebo-controlled trial

BACKGROUND: A subgroup of depressed patients with increased inflammatory activity was shown to be more susceptible to develop Treatment Resistant Depression (TRD). Earlier studies with anti-inflammatory drugs have shown benefits in the treatment of major depressive disorder (MDD), but the effects ar...

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Detalles Bibliográficos
Autores principales: Yang, Chenghao, Bosker, Fokko J., Li, Jie, Schoevers, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122706/
https://www.ncbi.nlm.nih.gov/pubmed/30176835
http://dx.doi.org/10.1186/s12888-018-1845-1