Population pharmacokinetics of mefloquine given as a 3-day artesunate–mefloquine in patients with acute uncomplicated Plasmodium falciparum malaria in a multidrug-resistant area along the Thai–Myanmar border

BACKGROUND: Low mefloquine exposure has been shown to contribute to treatment failure in patients with uncomplicated falciparum malaria following a 3-day artesunate–mefloquine combination. The present study aimed to develop a population pharmacokinetic model for mefloquine based on whole blood conce...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoglund, Richard M., Ruengweerayut, Ronnatrai, Na-Bangchang, Kesara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122721/
https://www.ncbi.nlm.nih.gov/pubmed/30176888
http://dx.doi.org/10.1186/s12936-018-2466-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122721/
https://www.ncbi.nlm.nih.gov/pubmed/30176888
http://dx.doi.org/10.1186/s12936-018-2466-3

Ejemplares similares