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Effect of metformin on the survival of patients with ALL who express high levels of the ABCB1 drug resistance gene

BACKGROUND: In acute lymphoblastic leukemia (ALL), high ABCB1 gene expression has been associated with treatment resistance, which affects patient prognosis. Many preclinical reports and retrospective population studies have shown an anti-cancer effect of metformin. Therefore, the objective of this...

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Detalles Bibliográficos
Autores principales:	Ramos-Peñafiel, Christian, Olarte-Carrillo, Irma, Cerón-Maldonado, Rafael, Rozen-Fuller, Etta, Kassack-Ipiña, Juan Julio, Meléndez-Mier, Guillermo, Collazo-Jaloma, Juan, Martínez-Tovar, Adolfo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122769/ https://www.ncbi.nlm.nih.gov/pubmed/30176891 http://dx.doi.org/10.1186/s12967-018-1620-6

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