Overexpression of the VRK1 kinase, which is associated with breast cancer, induces a mesenchymal to epithelial transition in mammary epithelial cells

Vaccinia-related kinase 1 (VRK1) is a pro-proliferative nuclear kinase. Mice engrafted with VRK1-depleted MDA-MB-231 breast cancer cells have been shown to develop fewer distal metastases than controls, suggesting VRK1 might play a role in cell migration, invasion, and/or colonization. In work descr...

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Detalles Bibliográficos
Autores principales: Mon, Aye M., MacKinnon, A. Craig, Traktman, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122820/
https://www.ncbi.nlm.nih.gov/pubmed/30180179
http://dx.doi.org/10.1371/journal.pone.0203397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122820/
https://www.ncbi.nlm.nih.gov/pubmed/30180179
http://dx.doi.org/10.1371/journal.pone.0203397

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