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Computational screening of known broad-spectrum antiviral small organic molecules for potential influenza HA stem inhibitors

BACKGROUND: With the emergence of new influenza virus strains that are resistant to current inhibitors such as oseltamivir (anti-neuraminidase (NA)) and amantadine (anti-M2 proton channel), influenza A viruses continue to be a serious threat to the public health worldwide. With this in view, there i...

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Detalles Bibliográficos
Autores principales: Mathew, Shilu, Al Thani, Asmaa A., Yassine, Hadi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122827/
https://www.ncbi.nlm.nih.gov/pubmed/30180218
http://dx.doi.org/10.1371/journal.pone.0203148