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Computational screening of known broad-spectrum antiviral small organic molecules for potential influenza HA stem inhibitors
BACKGROUND: With the emergence of new influenza virus strains that are resistant to current inhibitors such as oseltamivir (anti-neuraminidase (NA)) and amantadine (anti-M2 proton channel), influenza A viruses continue to be a serious threat to the public health worldwide. With this in view, there i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122827/ https://www.ncbi.nlm.nih.gov/pubmed/30180218 http://dx.doi.org/10.1371/journal.pone.0203148 |