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NLRC3 negatively regulates CD4(+) T cells and impacts protective immunity during Mycobacterium tuberculosis infection
NLRC3, a member of the NLR family, has been reported as a negative regulator of inflammatory signaling pathways in innate immune cells. However, the direct role of NLRC3 in modulation of CD4(+) T-cell responses in infectious diseases has not been studied. In the present study, we showed that NLRC3 p...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122840/ https://www.ncbi.nlm.nih.gov/pubmed/30133544 http://dx.doi.org/10.1371/journal.ppat.1007266 |