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Targeting Prion-like Cis Phosphorylated Tau Pathology in Neurodegenerative Diseases

Tau is a microtubule-associated protein heavily implicated in neurodegenerative diseases collectively known as tauopathies, including Alzheimer’s disease and chronic traumatic encephalopathy. Phosphorylation of tau at Thr231 allows for the isomerization of phosphorylated tau (p-tau) into distinct ci...

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Detalles Bibliográficos
Autores principales: Albayram, Onder, Angeli, Peter, Bernstein, Elizabeth, Baxley, Sean, Gao, Ziang, Lu, Kun Ping, Zhou, Xiao Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122852/
https://www.ncbi.nlm.nih.gov/pubmed/30197831
http://dx.doi.org/10.4172/2161-0460.1000443