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Antitumor effect of gemcitabine-loaded albumin nanoparticle on gemcitabine-resistant pancreatic cancer induced by low hENT1 expression

PURPOSE: Gemcitabine is currently the standard first-line chemotherapeutic drug for treating pancreatic cancer. However, many factors can contribute to gemcitabine resistance. One of the most important reasons is the low hENT1 expression. In this study, we tested the antitumor effect of gemcitabine-...

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Detalles Bibliográficos
Autores principales: Guo, Zhongyi, Wang, Feng, Di, Yang, Yao, Lie, Yu, Xinzhe, Fu, Deliang, Li, Ji, Jin, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122898/
https://www.ncbi.nlm.nih.gov/pubmed/30214194
http://dx.doi.org/10.2147/IJN.S166769