Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites

Voltage-gated sodium (Na(V)) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic Na(V) channel NaChBac have demonstrated that propofol promotes channel activation and accelerates activation-coupled inactiv...

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Detalles Bibliográficos
Autores principales: Wang, Yali, Yang, Elaine, Wells, Marta M., Bondarenko, Vasyl, Woll, Kellie, Carnevale, Vincenzo, Granata, Daniele, Klein, Michael L., Eckenhoff, Roderic G., Dailey, William P., Covarrubias, Manuel, Tang, Pei, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122922/
https://www.ncbi.nlm.nih.gov/pubmed/30018039
http://dx.doi.org/10.1085/jgp.201811993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122922/
https://www.ncbi.nlm.nih.gov/pubmed/30018039
http://dx.doi.org/10.1085/jgp.201811993

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