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PLC and IP(3)-evoked Ca(2+) release initiate the fast block to polyspermy in Xenopus laevis eggs

The prevention of polyspermy is essential for the successful progression of normal embryonic development in most sexually reproducing species. In external fertilizers, the process of fertilization induces a depolarization of the egg’s membrane within seconds, which inhibits supernumerary sperm from...

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Detalles Bibliográficos
Autores principales: Wozniak, Katherine L., Tembo, Maiwase, Phelps, Wesley A., Lee, Miler T., Carlson, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122927/
https://www.ncbi.nlm.nih.gov/pubmed/30012841
http://dx.doi.org/10.1085/jgp.201812069