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The human CIB1–EVER1–EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses

Patients with epidermodysplasia verruciformis (EV) and biallelic null mutations of TMC6 (encoding EVER1) or TMC8 (EVER2) are selectively prone to disseminated skin lesions due to keratinocyte-tropic human β-papillomaviruses (β-HPVs), which lack E5 and E8. We describe EV patients homozygous for null...

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Detalles Bibliográficos
Autores principales: de Jong, Sarah Jill, Créquer, Amandine, Matos, Irina, Hum, David, Gunasekharan, Vignesh, Lorenzo, Lazaro, Jabot-Hanin, Fabienne, Imahorn, Elias, Arias, Andres A., Vahidnezhad, Hassan, Youssefian, Leila, Markle, Janet G., Patin, Etienne, D’Amico, Aurelia, Wang, Claire Q.F., Full, Florian, Ensser, Armin, Leisner, Tina M., Parise, Leslie V., Bouaziz, Matthieu, Maya, Nataly Portilla, Cadena, Xavier Rueda, Saka, Bayaki, Saeidian, Amir Hossein, Aghazadeh, Nessa, Zeinali, Sirous, Itin, Peter, Krueger, James G., Laimins, Lou, Abel, Laurent, Fuchs, Elaine, Uitto, Jouni, Franco, Jose Luis, Burger, Bettina, Orth, Gérard, Jouanguy, Emmanuelle, Casanova, Jean-Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122964/
https://www.ncbi.nlm.nih.gov/pubmed/30068544
http://dx.doi.org/10.1084/jem.20170308