Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome

Metabolic programs are crucial for regulatory T (T reg) cell stability and function, but the underlying mechanisms that regulate T reg cell metabolism are elusive. Here, we report that lysosomal TRAF3IP3 acts as a pivotal regulator in the maintenance of T reg cell metabolic fitness. T reg–specific d...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoyan, Teng, Xiao-Lu, Wang, Feixiang, Zheng, Yuhan, Qu, Guojun, Zhou, Yan, Hu, Zhilin, Wu, Zhongqiu, Chang, Yuzhou, Chen, Lei, Li, Hua-Bing, Su, Bing, Lu, Liming, Liu, Zhiduo, Sun, Shao-Cong, Zou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122976/
https://www.ncbi.nlm.nih.gov/pubmed/30115741
http://dx.doi.org/10.1084/jem.20180397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122976/
https://www.ncbi.nlm.nih.gov/pubmed/30115741
http://dx.doi.org/10.1084/jem.20180397

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