Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau

Alzheimer’s disease (AD) is an age-associated neurodegenerative disease characterized by amyloidosis, tauopathy, and activation of microglia, the brain resident innate immune cells. We show that a RiboTag translational profiling approach can bypass biases due to cellular enrichment/cell sorting. Usi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Silvia S., Ebbert, Mark T.W., Baker, Kelsey E., Cook, Casey, Wang, Xuewei, Sens, Jonathon P., Kocher, Jeanne-Pierre, Petrucelli, Leonard, Fryer, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978/
https://www.ncbi.nlm.nih.gov/pubmed/30082275
http://dx.doi.org/10.1084/jem.20180653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978/
https://www.ncbi.nlm.nih.gov/pubmed/30082275
http://dx.doi.org/10.1084/jem.20180653

Ejemplares similares