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A NUMB–EFA6B–ARF6 recycling route controls apically restricted cell protrusions and mesenchymal motility

The endocytic protein NUMB has been implicated in the control of various polarized cellular processes, including the acquisition of mesenchymal migratory traits through molecular mechanisms that have only been partially defined. Here, we report that NUMB is a negative regulator of a specialized set...

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Detalles Bibliográficos
Autores principales: Zobel, Martina, Disanza, Andrea, Senic-Matuglia, Francesca, Franco, Michel, Colaluca, Ivan Nicola, Confalonieri, Stefano, Bisi, Sara, Barbieri, Elisa, Caldieri, Giusi, Sigismund, Sara, Pece, Salvatore, Chavrier, Philippe, Di Fiore, Pier Paolo, Scita, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123001/
https://www.ncbi.nlm.nih.gov/pubmed/30061108
http://dx.doi.org/10.1083/jcb.201802023