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A NUMB–EFA6B–ARF6 recycling route controls apically restricted cell protrusions and mesenchymal motility
The endocytic protein NUMB has been implicated in the control of various polarized cellular processes, including the acquisition of mesenchymal migratory traits through molecular mechanisms that have only been partially defined. Here, we report that NUMB is a negative regulator of a specialized set...
Autores principales: | Zobel, Martina, Disanza, Andrea, Senic-Matuglia, Francesca, Franco, Michel, Colaluca, Ivan Nicola, Confalonieri, Stefano, Bisi, Sara, Barbieri, Elisa, Caldieri, Giusi, Sigismund, Sara, Pece, Salvatore, Chavrier, Philippe, Di Fiore, Pier Paolo, Scita, Giorgio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123001/ https://www.ncbi.nlm.nih.gov/pubmed/30061108 http://dx.doi.org/10.1083/jcb.201802023 |
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