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Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop

Drosophila melanogaster neural stem cells (neuroblasts [NBs]) divide asymmetrically by differentially segregating protein determinants into their daughter cells. Although the machinery for asymmetric protein segregation is well understood, the events that reprogram one of the two daughter cells towa...

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Detalles Bibliográficos
Autores principales: Wissel, Sebastian, Harzer, Heike, Bonnay, François, Burkard, Thomas R., Neumüller, Ralph A., Knoblich, Juergen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123005/
https://www.ncbi.nlm.nih.gov/pubmed/29959232
http://dx.doi.org/10.1083/jcb.201711167