Pioglitazone, a PPAR-γ Activator, Stimulates BK(Ca) but Suppresses IK(M) in Hippocampal Neurons

Pioglitazone (PIO), a thiazolidinedone, was reported to stimulate peroxisome proliferator-activated receptor-γ (PPAR-γ) with anti-inflammatory, anti-proliferative, anti-diabetic, and antidepressive activities. However, whether this compound exerts any perturbations on Ca(2+)-activated K(+) and M-typ...

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Detalles Bibliográficos
Autores principales: Chen, Tsang-Shan, Lai, Ming-Chi, Hung, Te-Yu, Lin, Kao-Min, Huang, Chin-Wei, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123368/
https://www.ncbi.nlm.nih.gov/pubmed/30210346
http://dx.doi.org/10.3389/fphar.2018.00977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123368/
https://www.ncbi.nlm.nih.gov/pubmed/30210346
http://dx.doi.org/10.3389/fphar.2018.00977

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