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Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis
Astrocytes have emerged as critical elements for the maintenance and function of the central nervous system. The expression on their cell membrane of RAGE and TLR4 receptors makes astrocytes susceptible to High-mobility group box 1 (HMGB1), a nuclear protein typically released in the extracellular m...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123379/ https://www.ncbi.nlm.nih.gov/pubmed/30210286 http://dx.doi.org/10.3389/fnins.2018.00622 |