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Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens

Development of effective antimicrobial agents continues to be a great challenge, particularly due to the increasing resistance of superbugs and frequent hospital breakouts. There is an urgent need for more potent and safer antibiotics with novel scaffolds. As historically many commercial drugs were...

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Detalles Bibliográficos
Autores principales: Lin, Zihua, Xu, Xiaobo, Zhao, Sheng, Yang, Xiaohong, Guo, Jian, Zhang, Qun, Jing, Chunmei, Chen, Shawn, He, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123416/
https://www.ncbi.nlm.nih.gov/pubmed/30181560
http://dx.doi.org/10.1038/s41467-018-05821-1