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Polymorphisms of SLCO1B1 rs4149056 and SLC22A1 rs2282143 are associated with responsiveness to acitretin in psoriasis patients

Acitretin is widely used to treat psoriasis, but the efficacy varies significantly among individuals. To explore the association between polymorphisms and acitretin efficacy, we enrolled 46 and 105 Chinese Han psoriasis vulgaris patients for discovery and validation phases, respectively. The patient...

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Detalles Bibliográficos
Autores principales: Chen, Wangqing, Zhang, Xu, Zhang, Wei, Peng, Cong, Zhu, Wu, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123456/
https://www.ncbi.nlm.nih.gov/pubmed/30181619
http://dx.doi.org/10.1038/s41598-018-31352-2