Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1

A family of DEDDh 3′→5′ exonucleases known as Small RNA Degrading Nucleases (SDNs) initiates the turnover of ARGONAUTE1 (AGO1)-bound microRNAs in Arabidopsis by trimming their 3′ ends. Here, we report the crystal structure of Arabidopsis SDN1 (residues 2-300) in complex with a 9 nucleotide single-st...

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Detalles Bibliográficos
Autores principales: Chen, Jiayi, Liu, Li, You, Chenjiang, Gu, Jiaqi, Ruan, Wenjie, Zhang, Lu, Gan, Jianhua, Cao, Chunyang, Huang, Ying, Chen, Xuemei, Ma, Jinbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123492/
https://www.ncbi.nlm.nih.gov/pubmed/30181559
http://dx.doi.org/10.1038/s41467-018-05942-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123492/
https://www.ncbi.nlm.nih.gov/pubmed/30181559
http://dx.doi.org/10.1038/s41467-018-05942-7

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