The Telomerase Complex Directly Controls Hematopoietic Stem Cell Differentiation and Senescence in an Induced Pluripotent Stem Cell Model of Telomeropathy

Telomeropathies are rare disorders associated with impaired telomere length control mechanisms that frequently result from genetic mutations in the telomerase complex. Dyskeratosis congenita is a congenital progressive telomeropathy in which mutation in the telomerase RNA component (TERC) impairs te...

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Detalles Bibliográficos
Autores principales: Jose, Shyam Sushama, Tidu, Federico, Burilova, Petra, Kepak, Tomas, Bendickova, Kamila, Fric, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123533/
https://www.ncbi.nlm.nih.gov/pubmed/30210531
http://dx.doi.org/10.3389/fgene.2018.00345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123533/
https://www.ncbi.nlm.nih.gov/pubmed/30210531
http://dx.doi.org/10.3389/fgene.2018.00345

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