BK channel deacetylation by SIRT1 in dentate gyrus regulates anxiety and response to stress

Previous genomic studies in humans indicate that SIRT1, a nicotinamide adenine dinucleotide (NAD+)-dependent protein deacetylase, is involved in anxiety and depression, but the mechanisms are unclear. We previously showed that SIRT1 is highly activated in the nuclear fraction of the dentate gyrus of...

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Detalles Bibliográficos
Autores principales: Yu, Diankun, Homiack, Damek R., Sawyer, Edward J., Schrader, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123630/
https://www.ncbi.nlm.nih.gov/pubmed/30271963
http://dx.doi.org/10.1038/s42003-018-0088-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123630/
https://www.ncbi.nlm.nih.gov/pubmed/30271963
http://dx.doi.org/10.1038/s42003-018-0088-5

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