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Molecular phenotyping of laboratory mouse strains using 500 multiple reaction monitoring mass spectrometry plasma assays

Mouse is the predominant experimental model for the study of human disease due, in part, to phylogenetic relationship, ease of breeding, and the availability of molecular tools for genetic manipulation. Advances in genome-editing methodologies, such as CRISPR-Cas9, enable the rapid production of new...

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Detalles Bibliográficos
Autores principales: Michaud, Sarah A., Sinclair, Nicholas J., Pětrošová, Helena, Palmer, Andrea L., Pistawka, Adam J., Zhang, Suping, Hardie, Darryl B., Mohammed, Yassene, Eshghi, Azad, Richard, Vincent R., Sickmann, Albert, Borchers, Christoph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123701/
https://www.ncbi.nlm.nih.gov/pubmed/30271959
http://dx.doi.org/10.1038/s42003-018-0087-6