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Molecular phenotyping of laboratory mouse strains using 500 multiple reaction monitoring mass spectrometry plasma assays
Mouse is the predominant experimental model for the study of human disease due, in part, to phylogenetic relationship, ease of breeding, and the availability of molecular tools for genetic manipulation. Advances in genome-editing methodologies, such as CRISPR-Cas9, enable the rapid production of new...
Autores principales: | Michaud, Sarah A., Sinclair, Nicholas J., Pětrošová, Helena, Palmer, Andrea L., Pistawka, Adam J., Zhang, Suping, Hardie, Darryl B., Mohammed, Yassene, Eshghi, Azad, Richard, Vincent R., Sickmann, Albert, Borchers, Christoph H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123701/ https://www.ncbi.nlm.nih.gov/pubmed/30271959 http://dx.doi.org/10.1038/s42003-018-0087-6 |
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