Recombinant human B cell repertoires enable screening for rare, specific, and natively paired antibodies

The human antibody repertoire is increasingly being recognized as a valuable source of therapeutic grade antibodies. However, methods for mining primary antibody-expressing B cells are limited in their ability to rapidly isolate rare and antigen-specific binders. Here we show the encapsulation of tw...

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Detalles Bibliográficos
Autores principales: Rajan, Saravanan, Kierny, Michael R., Mercer, Andrew, Wu, Jincheng, Tovchigrechko, Andrey, Wu, Herren, Dall′Acqua, William F., Xiao, Xiaodong, Chowdhury, Partha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123710/
https://www.ncbi.nlm.nih.gov/pubmed/30271892
http://dx.doi.org/10.1038/s42003-017-0006-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123710/
https://www.ncbi.nlm.nih.gov/pubmed/30271892
http://dx.doi.org/10.1038/s42003-017-0006-2

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