Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope

Transient interactions in which binding partners retain substantial conformational disorder play an essential role in regulating biological networks, challenging the expectation that specificity demands structurally defined and unambiguous molecular interactions. The monoclonal antibody 6D8 recognis...

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Detalles Bibliográficos
Autores principales: Krishnarjuna, Bankala, Sugiki, Toshihiko, Morales, Rodrigo A. V., Seow, Jeffrey, Fujiwara, Toshimichi, Wilde, Karyn L., Norton, Raymond S., MacRaild, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123721/
https://www.ncbi.nlm.nih.gov/pubmed/30271940
http://dx.doi.org/10.1038/s42003-018-0063-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123721/
https://www.ncbi.nlm.nih.gov/pubmed/30271940
http://dx.doi.org/10.1038/s42003-018-0063-1

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