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Multiple claudin–claudin cis interfaces are required for tight junction strand formation and inherent flexibility

Tight junctions consist of a network of sealing strands that create selective ion permeability barriers between adjoining epithelial or endothelial cells. The current model for tight junction strands consists of paired rows of claudins (Cldn) coupled by a cis interface (X-1) derived from crystalline...

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Detalles Bibliográficos
Autores principales: Zhao, Jun, Krystofiak, Evan S., Ballesteros, Angela, Cui, Runjia, Van Itallie, Christina M., Anderson, James M., Fenollar-Ferrer, Cristina, Kachar, Bechara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123731/
https://www.ncbi.nlm.nih.gov/pubmed/30271933
http://dx.doi.org/10.1038/s42003-018-0051-5