Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research

Orphan G-protein-coupled receptors (oGPCRs) possess untapped potential for drug discovery. In the brain, oGPCRs are generally expressed at low abundance and their function is understudied. Expression profiling is an essential step to position oGPCRs in brain function and disease, however public data...

Descripción completa

Detalles Bibliográficos
Autores principales: Ehrlich, Aliza T., Maroteaux, Grégoire, Robe, Anne, Venteo, Lydie, Nasseef, Md. Taufiq, van Kempen, Leon C., Mechawar, Naguib, Turecki, Gustavo, Darcq, Emmanuel, Kieffer, Brigitte L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123746/
https://www.ncbi.nlm.nih.gov/pubmed/30271982
http://dx.doi.org/10.1038/s42003-018-0106-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123746/
https://www.ncbi.nlm.nih.gov/pubmed/30271982
http://dx.doi.org/10.1038/s42003-018-0106-7

Ejemplares similares