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Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research
Orphan G-protein-coupled receptors (oGPCRs) possess untapped potential for drug discovery. In the brain, oGPCRs are generally expressed at low abundance and their function is understudied. Expression profiling is an essential step to position oGPCRs in brain function and disease, however public data...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123746/ https://www.ncbi.nlm.nih.gov/pubmed/30271982 http://dx.doi.org/10.1038/s42003-018-0106-7 |