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Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice

Eosinophil degranulation is a determining factor in allergy-mediated airway pathology. Receptor-mediated degranulation in eosinophils requires vesicle-associated membrane protein 7 (VAMP-7), a principal component of the SNARE fusion machinery. The specific contribution of eosinophil degranulation to...

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Detalles Bibliográficos
Autores principales: Willetts, Lian, Felix, Lindsey C., Jacobsen, Elizabeth A., Puttagunta, Lakshmi, Condjella, Rachel M., Zellner, Katie R., Ochkur, Sergei I., Kim, John D., Luo, Huijun, Lee, Nancy A., Lee, James J., Moqbel, Redwan, Lacy, Paige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123774/
https://www.ncbi.nlm.nih.gov/pubmed/30271964
http://dx.doi.org/10.1038/s42003-018-0081-z