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Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice
Eosinophil degranulation is a determining factor in allergy-mediated airway pathology. Receptor-mediated degranulation in eosinophils requires vesicle-associated membrane protein 7 (VAMP-7), a principal component of the SNARE fusion machinery. The specific contribution of eosinophil degranulation to...
Autores principales: | Willetts, Lian, Felix, Lindsey C., Jacobsen, Elizabeth A., Puttagunta, Lakshmi, Condjella, Rachel M., Zellner, Katie R., Ochkur, Sergei I., Kim, John D., Luo, Huijun, Lee, Nancy A., Lee, James J., Moqbel, Redwan, Lacy, Paige |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123774/ https://www.ncbi.nlm.nih.gov/pubmed/30271964 http://dx.doi.org/10.1038/s42003-018-0081-z |
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