Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis

Triple-negative breast cancer (TNBC) is a highly metastatic breast cancer with poor prognosis. In the present study, we demonstrated that Src, a non-receptor tyrosine kinase, might provide an effective therapeutic strategy to overcome TNBC invasion and metastasis, which are mediated via the synergis...

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Detalles Bibliográficos
Autores principales: Gautam, Jaya, Banskota, Suhrid, Lee, Hyunji, Lee, Yu-Jeong, Jeon, Yong Hyun, Kim, Jung-Ae, Jeong, Byeong-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123788/
https://www.ncbi.nlm.nih.gov/pubmed/30185799
http://dx.doi.org/10.1038/s12276-018-0135-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123788/
https://www.ncbi.nlm.nih.gov/pubmed/30185799
http://dx.doi.org/10.1038/s12276-018-0135-9

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