The EphA2 receptor is activated through induction of distinct, ligand-dependent oligomeric structures

The EphA2 receptor tyrosine kinase is capable of activating multiple diverse signaling pathways with roles in processes such as tissue homeostasis and cancer. EphA2 is known to form activated oligomers in the presence of ephrin-A ligands. Here, we characterize the lateral interactions between full-l...

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Detalles Bibliográficos
Autores principales: Singh, Deo R., Kanvinde, Pranjali, King, Christopher, Pasquale, Elena B., Hristova, Kalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123813/
https://www.ncbi.nlm.nih.gov/pubmed/30271902
http://dx.doi.org/10.1038/s42003-018-0017-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123813/
https://www.ncbi.nlm.nih.gov/pubmed/30271902
http://dx.doi.org/10.1038/s42003-018-0017-7

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