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Sulbactam-enhanced cytotoxicity of doxorubicin in breast cancer cells
BACKGROUND: Multidrug resistance (MDR) is a major obstacle in breast cancer treatment. The predominant mechanism underlying MDR is an increase in the activity of adenosine triphosphate (ATP)-dependent drug efflux transporters. Sulbactam, a β-lactamase inhibitor, is generally combined with β-lactam a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123926/ https://www.ncbi.nlm.nih.gov/pubmed/30202239 http://dx.doi.org/10.1186/s12935-018-0625-9 |