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Complement activation contributes to perioperative neurocognitive disorders in mice

BACKGROUND: The complement system plays an important role in many neurological disorders. Complement modulation, including C3/C3a receptor signaling, shows promising therapeutic effects on cognition and neurodegeneration. Yet, the implications for this pathway in perioperative neurocognitive disorde...

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Detalles Bibliográficos
Autores principales: Xiong, Chao, Liu, Jinhu, Lin, Dandan, Zhang, Juxia, Terrando, Niccolò, Wu, Anshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123969/
https://www.ncbi.nlm.nih.gov/pubmed/30180861
http://dx.doi.org/10.1186/s12974-018-1292-4