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(1,3)-β-D-glucan-based diagnosis of invasive Candida infection versus culture-based diagnosis in patients with sepsis and with an increased risk of invasive Candida infection (CandiSep): study protocol for a randomized controlled trial

BACKGROUND: The time to diagnosis of invasive Candida infection (ICI) is often too long to initiate timely antifungal therapy in patients with sepsis. Elevated serum (1,3)-β-D-glucan (BDG) concentrations have a high diagnostic sensitivity for detecting ICI. However, the clinical significance of elev...

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Detalles Bibliográficos
Autores principales: Bloos, Frank, Held, Jürgen, Schlattmann, Peter, Brillinger, Nicole, Kurzai, Oliver, Cornely, Oliver A., Thomas-Rüddel, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124015/
https://www.ncbi.nlm.nih.gov/pubmed/30180873
http://dx.doi.org/10.1186/s13063-018-2868-0