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A mathematical understanding of how cytoplasmic dynein walks on microtubules

Cytoplasmic dynein 1 (hereafter referred to simply as dynein) is a dimeric motor protein that walks and transports intracellular cargos towards the minus end of microtubules. In this article, we formulate, based on physical principles, a mechanical model to describe the stepping behaviour of cytopla...

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Detalles Bibliográficos
Autores principales: Trott, L., Hafezparast, M., Madzvamuse, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124060/
https://www.ncbi.nlm.nih.gov/pubmed/30224978
http://dx.doi.org/10.1098/rsos.171568