Dexmedetomidine attenuates cerebral ischemia/reperfusion injury in neonatal rats by inhibiting TLR4 signaling

OBJECTIVE: The sedative dexmedetomidine plays a role in multi-organ protection by inhibiting toll-like receptor (TLR) 4 expression in ischemia/reperfusion injury. The present study investigated whether the neuroprotective effects of dexmedetomidine could be blocked by the TLR4 agonist lipopolysaccha...

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Detalles Bibliográficos
Autores principales: Cheng, Jiangxia, Zhu, Pengfei, Qin, Han, Li, Xia, Yu, Hai, Yu, Hui, Peng, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Pre-Clinical Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124261/
https://www.ncbi.nlm.nih.gov/pubmed/29926753
http://dx.doi.org/10.1177/0300060518781382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124261/
https://www.ncbi.nlm.nih.gov/pubmed/29926753
http://dx.doi.org/10.1177/0300060518781382

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