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Isoflurane decreases interleukin-2 production by increasing c-Cbl and Cbl-b expression in rat peripheral blood mononuclear cells

OBJECTIVE: To evaluate how isoflurane affects T-cell function by assaying interleukin (IL)-2 production and the expression of two Casitas B-lineage lymphoma (Cbl) family proto-oncogenes (c-Cbl and Cbl-b) in rat peripheral blood mononuclear cells (PBMCs). METHODS: Adult male Sprague–Dawley rats were...

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Detalles Bibliográficos
Autores principales: Choi, Ji Won, Shin, Byung Seop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124271/
https://www.ncbi.nlm.nih.gov/pubmed/29938552
http://dx.doi.org/10.1177/0300060518770955